What is Gene homology?Gene homology is the study of organisms that have similar gene characteristics and makeup that have been passed down from a common ancestor [1] . In this case, I have looked at twelve organisms with a variety of epithelial linings to get an idea of how similar the length and structure of my various organisms of interest are. It was very likely that organisms that look similar to each other have the most similar homology, but sometimes you uncover a different results than expected. Using BLAST, PubMed and Clustal Omega, all of these similarities could be determined.
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Fruitfly (Drosophila melanogaster)
14-3-3zeta, transcript variant L, 1760bp Accession Number: NM_001273917.1 FASTA |
Discussion
The organisms above range in kingdom and type of animal, many primates have a higher identity than some of the other organisms. This gene is highly conserved in mammals and decreases over the time period. It is interesting to note that this gene localizes in the nucleus of the epithelial cells and plants do not have them. Further research could be done on the specific phenotypes found in each organism.
References:
[1] Homologous genes. (n.d.). Retrieved March 27, 2015, from http://evolution.berkeley.edu/evolibrary/article/1_0_0/eyes_10
[1] Homologous genes. (n.d.). Retrieved March 27, 2015, from http://evolution.berkeley.edu/evolibrary/article/1_0_0/eyes_10